Showing posts with label Success Rate. Show all posts
Showing posts with label Success Rate. Show all posts

Wednesday, September 2, 2009

Still in With a Chance

IVF Conception Still Possible


A visit to my IVF specialist revealed that he still thinks my husband and I will conceive. So despite being nearly 40 and despite my husbands sperm problems, he still thinks this is a realistic goal.

It's funny how a Doctor can be so confident when after 7 failures, you are not. So after asking all the probing questions, he still feels we will get pregnant. Apparently, he has done every test possible to me so from his perspective there is no reason why I should not fall pregnant. IVF apparently helps overcome male infertility issues so theoretically, there is no reason why we shouldn't be able to become parents.

This makes things a little frustrating as it seems everything that should be working isn't. I guess it puts us in no mans land. The other annoying thing is that IVF is not cheap - not by a long shot so every failure means spending more money on another round. Whilst, you can't put a cost on what I perceive to be a joy in having a baby, it does place a financial strain on your budget.

So with this in mind we have decided to continue down this path and try again. Fortunately, we have one frozen embryo left from the cycle I did in January. So apart from giving my body a rest from the drugs it means we will use our last remaining embryo. So if this fails, another stimulated cycle is on the cards. In the meantime, I will continue to focus on having a good nutritional diet, no alcohol or coffee - basically following the suggestions in the Pregnancy Miracle ebook I purchased a few weeks ago.

Thursday, August 27, 2009

What Biological Clock at 40

Back on Board for IVF at 40


Call me ignorant but after months of worrying about not being about to get pregnant before the age of 40, I am not worried anymore.

A sure sign of this is that after months of procastinating with the Police Record Check forms so I can start IVF, I have finally sent my form in complete with cheque. Somehow I don't think I will be getting it back in time for the 1st September deadline when the new laws take effect.

Apart from the fact that my husband's form has not been sent in yet, I imagine there will be a backlog of applications from the late rush of couples who have also submitted their forms. Obviously, holding off like me in the hope that they won't have to do another round of IVF. In any case, I guess it means we might start the next round a little later.

It's strange but I am less perturbed by the later start this time. In the past, I have pushed my body so hard, doing IVF with only a month break in between cycles. Once, I did a cycle back to back with no break. Now that was hard. All of my attempts, of course, have been done in my futile attempt to racie against my biological clock.

But the truth is, I will be turning 40 at the end of September. I am already in the statistically significant, lower end of the IVF success bracket. A delay of one month is hardly going to make a big difference. I think my body also needs a break to get back to its natural rhythm. The scary thing is that I've been doing this so frequently that I don't even know what my natural rhythm is.

Apart, from that IVF is hard - I am in no rush to start again only to get another negative result. I need emotional space to come to terms with the last seven failed attempts. Maybe my birthday this year will not be about trying to conceive - maybe it will be about relaxing and enjoying myself. Now that would be a nice change.

Friday, August 21, 2009

Questioning Your IVF Specialist

Questions to Ask After Repeated IVF Failures


After seven failed attempts at IVF, there comes a time when you have to ask some pretty hard questions to your Doctor.

I've been too frightened too ask - maybe I am not going to like what I might hear. But my visit with the Counsellor today did help in exploring what our options and questions we might ask our Doctor.

The questions are:
- Given our history and 7 failed attempts, what is the likelihood of us conceiving?
- Why do you think we lose so many embryos between day 3 and day 5?
- Do you think it has something to do with my egg quality or my husbands sperm?
- Should we try giving Day 3 embryos a go instead? (or Day 5 if relevant)
- Is there any kind of genetic testing that you think we should do?
- Are there any other tests that you think we should explore?
- Should my husband see an Andrologist?
- Should we have his sperm tested again?
- Are there any other alternatives that we should explore?

I am sure there are some that I have missed but these are the questions that seemed most relevant after repeated IVF failures.

Feel free to post any other questions you might have. We can all learn from other peoples questions.

Sunday, August 16, 2009

Embryo Debate Continues

Day 3 Versus Day 5 Embryos


The debate between Day 3 or Day 5 embryos continues. I have always done Day 5 blastocyst transfers. The theory being that scientists can monitor the embryo for longer so that they can assess which ones are most healthy. This allows them to process and screen out those embryos that are unlikely to survive and are the most healthier. Although, it is not that they are screened out - they just don't survive.

The risk is that you can lose most if not all of them. Certainly this is something we have experienced. From 19 eggs and 15 fertilised, we were left with only 1 Day 5 blastocyst. The implication being that if this failed to implant we would need to go through the whole process again.

We have now had 7 transfers in total (9 blastocysts) and every one of the them has failed to implant. They say that the definition of insanity is doing the same thing over again. Maybe we are insane. It led me to ask the question of my nurse, should we do day 3 transfers instead. Apart from the fact that she suggested I discuss this with my Doctor, her answer was interesting. She said some women have had no luck with Day 5 blastocysts and have tried Day 3 and got successfully pregnant. Others have had had the same result as Day 5. My guess is that there is no easy answer but I am going to give the Day 3 ones a go. Maybe there are better off in my body than some cultured medium.

Saturday, August 15, 2009

Getting Support Doing IVF

A Matter Of Counselling


Yesterday my nurse rang me to tell me the bad news that I already knew. My 5th IVF attempt was unsuccessful. I bombarded her with questions. Should I change Doctors, should I try Day 3 embryos instead of Day 5? Should I do this? Should I do that? In the process of asking questions, I burst into tears.

She was very understanding and asked me if I felt I needed to see a counsellor. I didn't know. I had mixed feelings about it when she asked. I am a strong person. I think I am coping fine but the last time and this time have hit me harder than the other times. Maybe I do need to see a counsellor. The thing is that I am grieving for someone that hasn't happened. No one has died. I know this makes it difficult for people to understand. But maybe I am grieving for the loss of hope or my dream of becoming a parent. Each failure brings this growing realisation that maybe my plans for parenthood are never to be. No - I am not giving up on IVF. I will persevere although I don't know for how long. What I do know is that each failure pushes you in this direction.

With some doubts, I agree to speak to a counsellor and I expect to hear from them next week. However, the Counsellor rang late Friday afternoon to arrange a time. This is happening too quickly but as it turns out, it is not. All Saturday appointments are booked out and the next available weekday appointment is Friday week in the afternoon. I check my work diary and there is a meeting organised. I decide there and then that I don't need to be there. I think I should accept the appointment. I think it is also in the interests of my employer that they have happy people working for them so will discuss this with my Manager when I return to work on Monday.

Oh and what were the answers to my questions. Now that's a long story and I am going to save that one for another day. Stay tuned.

Friday, August 14, 2009

How to Give Support

What Not to Say to Someone Undergoing IVF Treatment


IVF is unpredictable. My Doctor thinks I should be pregnant by now. This makes me feel a whole lot better. Not! The problem with IVF is that the more times you do it, the harder it gets. I am not exactly sure why but I think that statistically the majority of women get pregnant from IVF after 6-7 stimulated cycles. I have now done 5 stimulated cycles and two transfers and I've had no luck. This weight of expectation does not help.

The more you go on, the more there is an expectation that your turn is due. But IVF is never that simple. It makes it hard also for friends and family to understand what we are going through. Often people will say, don't give up. Keep trying. This is probably one of the worse things people can say.

They need to understand that when you get to the point of doing IVF you have already exhausted all other options - there is already a history of failed natural attempts. IVF gets harder the more times you do it. Apart from the money invested with nothing to show, there is also the physical demands on your body and living a life that has become less social and centred around your menstrual cycle and when and what drugs you are going to take. Life to some extent is on hold. You stay in a job with a manager who is critical and treats you badly because you need stability, you need your job to pay for IVF and you want to be eligible for maternity leave in the event you actually get pregnant.

There is also the fact that you are starting to reach a point where you feel you have no control over your body. It feels like your uterus is destined to become a graveyard.

The fact is that there is nothing anyone can say to their friend. Make it clear you are there for them if they need you but don't push it. All they can be is a friendly ear and a shoulder to cry on. Because as time goes on, that shoulder is most definitely needed.

Thursday, August 13, 2009

Bring Out the Bottle Again

Confirming IVF Failure


Just as I suspected. I am not pregnant. Another failed IVF cycle. Get me a drink now. A bottle of red or 3 will do nicely thanks.

Whilst my tell-tale breasts gave it all away, my sneaky suspicion was reinforced last night when giving myself a dose of Crinone gel. That suspicion was also confirmed at a visit to ladies room around lunch time today.

It's hard to believe that one could inspect toilet paper so thoroughly!!! Scouring through the folds to see if a flash of red has started to appear. Creepy I know but something any woman I know who hopes to get pregnant has done.

Another failed round of IVF. The last cycle was much more upsetting. After so many failures the expectation of pregnancy diminishes but the hope somehow gets stronger. Surely my turn will come. IVF is a numbers game - hopefully the more times you throw one in, eventually your odds come up. To add insult to the wound, I also have to sit through yet another blood test tomorrow to tell me what I already know. BFN (Big Fat Negative - for the uninitiated).

Expecting a week of intermittent tears. Interested friends - happy for you to make comments on this blog but please don't ask any questions or offer any condolences if seeing me in a public venue - it brings up too much emotion. Me thinks I deserve a red.

Perhaps this is an idea for tomorrow's blog - how friends can handle their fragile friends who are undergoing IVF. Now - where was that red. One glass will do fine given I have not had a drink in ages!!!!

Thursday, August 6, 2009

IVF On A Rollercoaster

Unpredictable Nature of IVF


A positive situation from yesterday has turned out to be not so positive today. Of the 13 embryos that we had yesterday, none survived!!! None. Not even the one that made it to early blastocyst stage. It is terrible. No fall backs. Nothing. Such is the unpredictable nature of IVF.

All our hopes are pinned on the one that was transferred yesterday. It is not a good situation to be in. If this one fails, then we know we are potentially going to face yet another cycle of IVF. I am not sure when a stopping point comes but sooner or later it has got to happen.

Friday, June 26, 2009

Frustrations of IVF

The Challenges of IVF


After 6 attempts at IVF, I have learnt that again I was not successful in getting pregnant. I was devastated and have had random moments of tears since that discovery.

I never thought that this week would be so hard. I am starting to learn that the the more you go down the IVF path, the harder it actually gets. I have now done 4 IVF stimulated cycles and 2 Frozen Embryo Transfers.

For my part, the disappointment stems from an unbelievable sense of loss. It feels like my dreams of becoming a parent will never materialize. My biological clock is ticking and my body is against me.

The difference with IVF compared to natural attempts at conception is the knowledge that an embryo has been implanted. What I mean is that you know an embryo is there and fertilisation has taken place. With this knowledge comes the hope that this time might be the lucky time. The disappointing thing, is that I now know that it isn't. I now have a history of two years of infertility and am contemplating doing another stimulated IVF cycle.

I am also surprised to learn new things about myself and depth of my emotions on the topic. I never thought this possible, but I am am surprised to learn that I would be a person who has been:
  • Happy but angry that a friend would conceive after 1 IVF stimulated cycle and 1 Frozen Embryo Transfer.
  • Reduced to tears when shopping for baby clothes at Target for a friend who recently gave birth because I am wondering if I will ever shop for clothes for my own baby.
  • Cynical (funny cause I've always been thought of as naive).
These are feelings that I would not normally have. I am even more devastated as we have going for top of the range blastocysts which according to my fertility specialist apparently has a better success rate than Day 3 embryos. I don't know how true this is - just look at what happened to my friend. What I do think however is that Day 5 embryos have a better chance of lining his pocket. Maybe that is the new "cynical' side of me coming out.

I hope that by writing this blog, I will then be able to help people understand more about IVF and the pressure that they or someone close to might go through if they go down this path. Whilst most IVF clinics explain about IVF from a technical viewpoint I believe that improvement could be made in helping couples understand the full ramifications of IVF. IVF is not the be all and end all. At best it offers people more hope and the potential to have children but it is by no means guaranteed.

In the meantime, my hats and commendations are for the women who have gone through far more cycles that I and who have had the courage to continue on. My commendations are also for the men who stood with them, all the while knowing how interfering IVF can be with your sex life and emotions.

In future blogs I intend to cover off what it is like going through a stimulated IVF cycle.